Há:
cx_Oracle
# Install --> You should have oracle installed otherwise exception will be raised
pip install cx_Oracle
import cx_Oracle
con = cx_Oracle.connect('pythonhol/welcome@127.0.0.1/orcl')
print con.version
con.close()
http://www.orafaq.com/wiki/Python
http://www.oracle.com/technetwork/articles/dsl /python-091105.html