select item_1 + item_2 + item_3 + item_4 as ItemSum
from MyTable
Se houver valores nulos, você precisará tratá-los assim:
select ifnull(item_1, 0) + ifnull(item_2, 0) + ifnull(item_3, 0) + ifnull(item_4, 0) as ItemSum
from MyTable
select item_1 + item_2 + item_3 + item_4 as ItemSum
from MyTable
select ifnull(item_1, 0) + ifnull(item_2, 0) + ifnull(item_3, 0) + ifnull(item_4, 0) as ItemSum
from MyTable