Adicione referências aos assemblies, adicione o atributo autogenerateschema="true" a ambos como:
<providers>
<remove name="MySQLProfileProvider"/>
<add name="MySQLProfileProvider" autogenerateschema="true" type="MySql.Web.Profile.MySQLProfileProvider, MySql.Web, Version=6.2.2.0, Culture=neutral, PublicKeyToken=c5687fc88969c44d" connectionStringName="LocalMySqlServer" applicationName="/"/>
</providers>
use a ferramenta de configuração ASP.Net.
